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Arrowhead Pharmaceuticals, Inc. (ARWR) Corporate Logo

Arrowhead Pharmaceuticals, Inc. (ARWR) Stock Price & Analysis

Market: NASDAQ • Sector: Healthcare • Industry: Biotechnology

Arrowhead Pharmaceuticals, Inc. (ARWR) Profile & Business Summary

Arrowhead Pharmaceuticals, Inc. develops medicines for the treatment of intractable diseases in the United States. The company's products in pipeline includes ARO-AAT, a RNA interference (RNAi) therapeutic candidate that is in Phase II clinical trial for the treatment of liver diseases associated with alpha-1 antitrypsin deficiency; ARO-APOC3, which is in phase 2b and one phase 3 clinical trial to treat hypertriglyceridemia; ARO-ANG3 that is in Phase 2b clinical trial to reduce production of angiopoietin-like protein 3; ARO-HSD, which is in Phase 1/2a clinical trial to treat liver diseases; ARO-ENaC, which is in a Phase 1/2a clinical trial to reduce production of the epithelial sodium channel alpha subunit in the airways of the lung; ARO-C3 for the treatment of complement-mediated disease that is in Phase 1/2a clinical trial; ARO-Lung2 for the treatment of chronic obstructive pulmonary disorder; ARO-DUX4 for the treatment of facioscapulohumeral muscular dystrophy; ARO-XDH to treat uncontrolled gout; ARO-COV for the treatment of COVID-19 and other pulmonary-borne pathogens; and ARO-HIF2, which is in phase 1b clinical trial to treat clear cell renal cell carcinoma. It is also involved in the development of JNJ-3989, a subcutaneously administered RNAi therapeutic candidate to treat chronic hepatitis B virus infection; Olpasiran to reduce the production of apolipoprotein A; and ARO-AMG1 for treating genetically validated cardiovascular targets. Arrowhead Pharmaceuticals, Inc. has a license and research collaboration agreement with Janssen Pharmaceuticals, Inc. to develop ARO-JNJ1, ARO-JNJ2, and ARO-JNJ3 RNAi therapeutics for liver-expressed targets; and license and research collaboration agreement with Takeda Pharmaceuticals U.S.A., Inc. to develop RNAi therapeutic candidate as a treatment for liver disease. Arrowhead Pharmaceuticals, Inc. was incorporated in 1989 and is headquartered in Pasadena, California.

Key Information

Ticker ARWR
Exchange NASDAQ
Official Site https://arrowheadpharma.com
CIK Number 0000879407
View SEC Filings

Market Trend Overview for ARWR

One model, two time views: what the market looks like right now, and where the larger trend is heading over time.

Longer-Term Market Trend (Mid to Long Term)

Shows the bigger market trend, how strong it is, and where risks may start to build over the next few weeks or months. — Updated as of 2026-10-13 (ET)

As of 2026-10-13, ARWR is showing signs of slowing down. Over the longer term, the trend remains bullish.

ARWR last closed at 58.13. The price is about 1.0 ATR below its recent average price (62.03), and the market is currently in a trend that may be losing strength. Price at 58.13 is near minor support around 53.76. Momentum may slow, while minor resistance sits near 62.99. View Support & Resistance from Options

Short-term weakness is unfolding within a broader uptrend, suggesting a pullback rather than a full trend reversal.

Trend Alignment Summary

Trend score: 55 out of 100. Overall alignment is unclear. The market is currently in a late-stage trend that may be losing strength. The longer-term trend is still positive, but short-term signals are not yet confirming it.

Key Risk Level

There is no clear key risk boundary right now.

Recent Trend Signal

On 2026-09-14, trend conditions deteriorated, suggesting that moves in the prior direction became less dependable.

Unusual Price Movement

[2026-10-12] Price moved quickly and looked strong, but participation was limited.

Recent Price Behavior

Recent bars show mixed price behavior without a clear shift in structural quality or efficiency.

Overnight Positioning

Closing activity showed limited conviction and did not suggest strong overnight positioning.

Next-day directional probability forecast Last updated: 2026-10-13 (ET)
Next-session outlook for 2026-10-14 (ET)
Bearish setup for the next session

What the model sees

The model sees a bearish edge, but still treats it as a selective downside setup rather than an aggressive downside call.


Why the model says this

Up probability is only 43.2%, with predictability at 49% and agreement at 100%. Reversal risk is 20%, while reward/risk stands at -0.19. That suggests downside pressure is present, while the setup still remains selective rather than extreme. At the same time, recent price behavior has shown failed reversal memory.

NOTE: This next-day up/down probability forecast module is still being tested for accuracy. Please do not rely on it for investment decisions. The model does not account for black swan events or company-specific fundamental news, and its estimates are based solely on technical conditions, capital flow, and market sentiment. View forecast history

Recent Cost Distribution Last updated: 2026-10-13 (ET)

This estimate uses 1-minute price, volume, and VWAP data from the last 58 trading days, with turnover-based decay. The sample period is 2026-07-23 to 2026-10-13. The current price is 58.13, 21.90% below the estimated average cost of 74.43. An estimated 0.0% of recent positioning is below the current price, while 99.9% is above it. The peak-density price is 65.70. The largest concentrated cost region is 64.65 to 68.35 and contains 29.0% of the estimated distribution. The nearest region above the current price is 58.75 to 58.85.

Short Interest & Covering Risk for ARWR

This analysis looks at overall short interest positioning, focusing on the broader setup rather than short-term noise.

Squeeze Score 0.71

Shows how likely a short squeeze may be under current market conditions.

Key Market Risk Indicators
Short Crowding (Short Interest / Float) 8.09%
Short Positions Trend Increasing
Liquidity Trend (Average Daily Volume) 34.56%
20-Day Return -17.74%
Price vs 20-Day High Below Recent Highs

Short Exposure Percentile

Short interest is well above normal levels, increasing the risk of forced covering and sudden price moves. (Historical percentile: 77%)

Structure Analysis

ARWR Short positioning looks normal. Current days to cover is 4.0 trading days, meaning short positions could unwind at a normal pace. Short covering is likely to have a normal impact on price moves. Price is already trending lower (20D return -17.7%). The current configuration reflects active downside pressure rather than latent structural fragility.

Risk Summary

No clear bull trap characteristics detected. Recent price behavior remains broadly consistent with current positioning.This reading helps confirm that current price action remains structurally healthy and does not indicate elevated trap risk.

Why Price Reactions May Be Stronger?

In the latest reporting period, short interest continues to increase. Price action is compressing (range is tightening), which can make breaks more sensitive. Adaptive thresholds applied to liquidity weakness, near-high detection, and compression sensitivity. As a result, similar news or market events could lead to price moves about 1× larger than usual.


Note: Short interest data is reported every two weeks by FINRA. The most recent snapshot is 2026-09-30 (ET).
Because this data updates slowly, it is not intended to predict short-term price moves. Instead, it helps describe longer-term market structure and where pressure may be building if prices begin to move.

Analytical Modules