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Vertex Pharmaceuticals Incorporated (VRTX) Corporate Logo

Vertex Pharmaceuticals Incorporated (VRTX) Stock Price & Analysis

Market: NASDAQ • Sector: Healthcare • Industry: Biotechnology

Vertex Pharmaceuticals Incorporated (VRTX) Profile & Business Summary

Vertex Pharmaceuticals Incorporated, a biotechnology company, engages in developing and commercializing therapies for treating cystic fibrosis. The company markets SYMDEKO/SYMKEVI, ORKAMBI, and KALYDECO to treat patients with cystic fibrosis who have specific mutations in their cystic fibrosis transmembrane conductance regulator gene; and TRIKAFTA for the treatment of patients with CF 6 years of age or older who have at least one F508del mutation. Its pipeline includes VX-864 for the treatment of AAT deficiency, which is in Phase 2 clinical trial; VX-147 for the treatment of APOL1-mediated focal segmental glomerulosclerosis, or FSGS, and other serious kidney diseases which is in Phase 2 clinical trial; VX- 880, treatment for Type 1 Diabetes which is in Phase 1/2 clinical trial; VX-548, a NaV1.8 inhibitor for treatments of acute, neuropathic, musculoskeletal pain which is in Phase 2 clinical trial; and CTX001 for the treatment severe SCD and TDT which is in Phase 3 clinical trial. The company sells its products primarily to specialty pharmacy and specialty distributors in the United States, as well as specialty distributors and retail chains, and hospitals and clinics internationally. It has collaborations with Affinia Therapeutics, Inc.; Arbor Biotechnologies, Inc.; CRISPR Therapeutics AG.; Kymera Therapeutics, Inc.; Mammoth Biosciences, Inc.; Moderna, Inc.; Obsidian Therapeutics, Inc.; and Skyhawk Therapeutics, Inc.; as well as Ribometrix, Inc.; Genomics plc; Merck KGaA; Darmstadt, Germany, and X-Chem, Inc. Vertex Pharmaceuticals Incorporated was founded in 1989 and is headquartered in Boston, Massachusetts.

Key Information

Ticker VRTX
Leadership Reshma Kewalramani
Exchange NASDAQ
Official Site https://www.vrtx.com
CIK Number 0000875320
View SEC Filings

Market Trend Overview for VRTX

One model, two time views: what the market looks like right now, and where the larger trend is heading over time.

Current Market Context (Short-Term)

As of 2026-02-06 (ET), VRTX is moving sideways. Price at 477.92 is moving between support near 443.12 and resistance near 485.00. There is no clear direction right now. View Support & Resistance from Options

Why the market looks this way?

Prices have moved back and forth over recent sessions without making steady progress. Trend signals have changed frequently, which suggests the market is stuck in a range. In this environment, chasing moves in either direction is less reliable.

Longer-Term Market Trend (Mid to Long Term)

Shows the bigger market trend, how strong it is, and where risks may start to build over the next few weeks or months. — Updated as of 2026-02-06 (ET)

As of 2026-02-06, VRTX is moving sideways without a clear direction. Over the longer term, the trend remains bullish.

VRTX last closed at 477.92. The price is about 1.5 ATR above its recent average price (463.82), and the market is currently in a sideways market without a clear direction.

The market is moving sideways, with no clear direction. Both upside and downside risks remain in play.

Trend Alignment Summary

Trend score: 35 out of 100. Overall alignment is unclear. The market is currently in a sideways market without a clear direction. The longer-term trend is still positive, but short-term signals are not yet confirming it.

Key Risk Level

A key downside level is near 432.79. If price falls below this area, the current upward trend would likely weaken or break.

Recent Trend Signal

A systematic trend-activation signal was most recently triggered on 2026-01-26, reflecting a technical shift toward positive directional alignment.

Unusual Price Movement

[2025-12-24] Price moved quickly and looked strong, but participation was limited.

Recent Price Behavior

Recent bars show mixed price behavior without a clear shift in structural quality or efficiency.

Overnight Positioning

Some late-day positioning was observed, but it lacked strong overnight commitment.

Short Interest & Covering Risk for VRTX

This analysis looks at overall short interest positioning, focusing on the broader setup rather than short-term noise.

Squeeze Score 0.75

Shows how likely a short squeeze may be under current market conditions.

Key Market Risk Indicators
Short Crowding (Short Interest / Float) 1.75%
Short Positions Trend Not Increasing
Liquidity Trend (Average Daily Volume) 0.00%
20-Day Return 1.75%
Price vs 20-Day High Trading Near Highs

Short Exposure Percentile

Short interest is within its typical range, with no clear imbalance between buyers and sellers. (Historical percentile: 50%)

Structure Analysis

VRTX Short positioning looks normal. Current days to cover is 3.1 trading days, meaning short positions could unwind at a normal pace. Short covering is likely to have a normal impact on price moves.

Bull Trap Structural Risk

Risk Summary

No clear bull trap characteristics detected. Recent price behavior remains broadly consistent with current positioning.This reading helps confirm that current price action remains structurally healthy and does not indicate elevated trap risk.

Why Price Reactions May Be Stronger?

Price is consolidating near highs with a weak upward bias, appearing strong on the surface but structurally more fragile. As a result, similar news or market events could lead to price moves about 1× larger than usual.

Note: Short interest data is reported every two weeks by FINRA. The most recent snapshot is 2026-01-15 (ET).
Because this data updates slowly, it is not intended to predict short-term price moves. Instead, it helps describe longer-term market structure and where pressure may be building if prices begin to move.

Analytical Modules